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BRL 44408
CAS No. 118343-19-4
BRL 44408( BRL44408 | BRL-44408 )
Catalog No. M10622 CAS No. 118343-19-4
A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBRL 44408
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.
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DescriptionA potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors; significantly increases stimulated noradrenaline release in rat locus coeruleus slices at 0.1-1 uM, significantly increases the electrically induced release in rats.
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In Vitro——
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In Vivo——
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SynonymsBRL44408 | BRL-44408
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorAdrenergic Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number118343-19-4
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Formula Weight215.3
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Molecular FormulaC13H17N3
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1C2=CC=CC=C2CN1CC3=NCCN3
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Chemical Name2-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,3-dihydro-1-methyl-1H-isoindole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kiss JP, et al. Brain Res. 1995 Mar 20;674(2):238-44.
2. Callado LF, et al. Eur J Pharmacol. 1999 Jan 29;366(1):35-9.
3. Young P, et al. Eur J Pharmacol. 1989 Sep 22;168(3):381-6.
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